New Azo-Schiff Compounds and Metal Complexes Derived from 2-Naphthol Synthesis, Characterization, Spectrophotometric, and Study of Biological Activity

This research involved synthesizing two compounds as derivatives of 2-naphthol by the classical method. The azo coupling compound was prepared via diazonium salt 4-amino acetophenone followed 2-naphthole. azo-Schiff molecule synthesized through condensation an with 5-amino salicylic acid in acidic medium. Using spectrum approaches, new are characterized (13C-NMR, 1H-NMR, FT-IR). acid-base characteristics were investigated at various pH levels (0.67-12), and ionization protonation constants determined. Spectroscopic methods used to identify copper (II), nickel cobalt (II) complexes base ligand. All evaluated for antibacterial activity against bacteria such Staphylococcus aureus (Gram-positive bacteria) Escherichia coli (Gram-negative bacteria). It found that coordination Cu Co had effect on both concentrations aureus.